
The Misfits, itself inspired by his child’s difficult experiences in middle school, was the inspiration behind GLSEN's annual No Name-Calling Week.

In 1997, he published his first young adult novel, The Watcher. In addition to the Bunnicula series, Howe has written picture books, children's novels, nonfiction, adaptations of classic stories, and screenplays for movies and television. Ten months before Bunnicula was published Deborah died, inspiring the creation of The Hospital Book. The book went on to win more than ten Children's Choice awards, including the Dorothy Canfield Fisher Award and the Nene Award, and eventually evolved into a series. With his wife, he created Bunnicula: A Rabbit Tale of Mystery, about a pet rabbit suspected of being a vampire. In the mid-1970s, Howe's mother-in-law encouraged him and his wife, Deborah Howe, to create a children's story based on a character the two had created while watching older Dracula movies, which at the time were played late at night on TVs.
Howe continued to write plays during his theater studies at Boston University, and eventually moved to New York City to pursue a career as an actor and model while directing plays and working as a literary agent. Of the latter his favorite is The Gory Gazette which he made for a self-founded club, Vampire Legion. At the age of nine or ten, Howe wrote a play based on the " Blondie" comic strip as well as a variety of short stories and self-published newspapers. He is best known for the Bunnicula series about a vampire rabbit that sucks the juice out of vegetables.

James Howe (born August 2, 1946) is an American children's writer who has written more than 79 juvenile and young adult fiction books.
